SEMINARIO QUÍMICA ORGÁNICA 11-11-24 EXPOSITOR : Qca. Paula Paz Armero TÍTULO : " Total synthesis of (±)‐decursivine via BINOL‐phosphoric acid catalyzed tandem oxidative cyclization ". FUENTE : PrakashT. Parvatkar, Eugene S. Smotkin & Roman Manetsc, Scientific Reports volume 11, Article number: 19915 (2021) DÍA, HORA y LUGAR : Lunes 11 de noviembre de 2024, 14:00 h, Aula 18 y virtual. Modalidad virtual, Link : meet.google.com/hjn-ygro-twf ( Plataforma MEET GOOGLE) Resumen : The synthesis of tetracyclic indole alkaloid (±)-decursivine was accomplished using BINOL-phosphoric acid catalyzed tandem oxidative cyclization as a key step with (bis(trifuoroacetoxy)iodo)benzene (PIFA) as an oxidizing agent. This represents one of the shortest and highest yielding routes for the synthesis of (±)-decursivine from readily available starting materials.