SEMINARIO QUÍMICA ORGÁNICA 12-5-25 EXPOSITOR : Dra. Agustina La Venia TÍTULO : " Recent Progress and Prospects of Small Molecules for NLRP3 Inflammasome Inhibition " FUENTE : Ying Chen, et al. Cell. Mol. Biol. Lett. 2023 , 28 , 51 . Na Li, et al. J. Med. Chem. 2023 , 66 , 14447-14473. DÍA, HORA y LUGAR : Lunes 12 de mayo de 2025, 14:00 h, Aula 18 y virtual. Modalidad virtual, Link : meet.google.com/hjn-ygro-twf ( Plataforma MEET GOOGLE) Resumen : NLRP3 inflammasome is a multiprotein complex involved in host immune response which exerts various biological effects by mediating the maturation and secretion of IL-1β and IL-18and pyroptosis. However, its aberrant activation could cause amplification of inflammatory effects, thereby triggering a range of ailments, including Alzheimer’s disease, Parkinson’s disease, rheumatoid arthritis, gout, type 2 diabetes mellitus, and cancer. For the past few years, as an attractive anti-inflammato...
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